---
title: "Chemical Manipulation of Humanity: Endocrine-Disrupting Chemical Exposure in Womb Impact Fear, Anxiety Behavior in Rats"
type: "post"
post_id: "2449"
slug: "chemical-manipulation-of-humanity-endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats"
canonical: "https://pennyforyourthoughts2.ca/2022/06/15/chemical-manipulation-of-humanity-endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats/"
markdown_url: "https://pennyforyourthoughts2.ca/2022/06/15/chemical-manipulation-of-humanity-endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats.md"
json_url: "https://pennyforyourthoughts2.ca/2022/06/15/chemical-manipulation-of-humanity-endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats.json"
txt_url: "https://pennyforyourthoughts2.ca/2022/06/15/chemical-manipulation-of-humanity-endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats.txt"
published: "2022-06-15T18:25:02+00:00"
modified: "2022-06-15T18:28:32+00:00"
author: "penny2"
categories:
  - "Uncategorized"
tags:
  - "Chemical Manipulation of Humanity"
  - "Science"
  - "state sponsored terrorism"
site_name: "PFYT2"
publisher: ""
language: "en-US"
generator: "easyPress Markdown"
generator_version: "1.0.6"
---
**This is a topic that was regularly featured at my big tech censored blog. Endocrine Disrupting Chemicals are the NUMBER 1- ENVIRONMENTAL ISSUE**

 **[Linked here](https://www.newswise.com/articles/endocrine-disrupting-chemical-exposure-in-womb-impact-fear-anxiety-behavior-in-rats) but originating with Endocrine Society**

> **Prenatal exposure to endocrine-disrupting chemicals found in everyday products may interfere with the developing offspring’s brain,** according to a rat study being presented Monday at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga.
> 
> P.S. MohanKumar, Ph.D., professor at the University of Georgia in Athens, Ga., and colleague**s, focused on the gestational effects of endocrine-disrupting chemicals bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP), and if they would change stress-related behaviors.**
> 
> ***“This research is significant because prenatal exposure to these chemicals may contribute to mood disorders later in life,”*** said study co-author Amrita Kaimal, Ph.D., of the University of Georgia Neuroscience Graduate Program.
> 
> A total of 76 Sprague-Dawley rats were used for the study. **After the rats were mated, pregnant female rats were administered oral saline, BPA, a combination of BPA and low-dose DEHP, or a combination of BPA and high-dose DEHP during days 6-21 of pregnancy. All of the doses were adjusted according to the body weight of the rat.**
> 
> **Behavioral tests were conducted in adult offspring, and brains from the rats were analyzed for monoamine neurotransmitters, like dopamine and serotonin.**
> 
> **Female offspring administered BPA and a combination of BPA and low-dose DEHP displayed less anxiety in the Open Field** Test, which measures activity and exploratory behavior. However, male offspring administered high-dose DEHP showed feminized anxiety-like behavior in a maze**`. Fear responses among male offspring in most of the groups exposed to endocrine-disrupting chemicals were impaired in a test examining the response to a threatening object. Interestingly, low-dose endocrine disruptors led to passive coping strategies in male and female offspring.`**
> 
> **`Brain studies indicate male offspring in the BPA, low-dose and high-dose DEHP, and BPA and high-dose DEHP groups had diminished dopamine levels in the paraventricular hypothalamic nucleus. This is associated with their impaired fear response.`**
> 
> “Our study confirms sex-specific behavioral changes in offspring as a result of these exposures, highlighting the fact that exposure to these chemicals should be avoided during pregnancy,” MohanKumar said.
> 
> MohanKumar will present at the Society’s ENDO 2022 endocrine-disrupting chemicals news conference at noon on Saturday, June 11. Register to attend the news conference at [www.endowebcasting.com](http://www.endowebcasting.com).